A decrease in Pa co co2 and H+ occurred in one of two patients with upper airway obstruction. There was no change or an increase in Pa co co2 and H+ in the subjects with lower airway obstruction and small increases in arterial oxygen saturation and Pa o o2 occurred. Alveolar ventilation decreased except when alveolar hypoventilation was present to start with. With tracheostomy breathing, the reduction in dead space led to a decrease in minute ventilation except in the two patients with upper airway obstruction. Journal of Applied Physiology The American Physiological Society Ībstract Acute experimentation to judge the effects of reduction of dead space with tracheostomy breathing was performed on four subjects with lower airway obstruction (bronchitis and emphysema) and on two subjects with upper airway obstruction (carcinoma of the larynx and tracheal stenosis). Note: (With the Technical Assistance of Roy Engstrom, Mabel Pearson, and Tom Purcell) physiological dead space and tracheostomy arterial blood gases with tracheostomy breathing tracheostomy versus mouth breathing emphysema and tracheostomy breathing Submitted on FebruCopyright © 1964 the American Physiological Society

Reduction of dead space per se with tracheostomy breathing brings about small changes in alveolar ventilation and gas exchange in the lungs of patients with chronic bronchitis and emphysema. Tracheostomy and respiratory dead space in emphysema Tracheostomy and respiratory dead space in emphysemaĪbstract Acute experimentation to judge the effects of reduction of dead space with tracheostomy breathing was performed on four subjects with lower airway obstruction (bronchitis and emphysema) and on two subjects with upper airway obstruction (carcinoma of the larynx and tracheal stenosis).

Physiologic dead space in emphysema